Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | AGER | Q15109 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6847922 | 0.91 | L3MBTL1 (0.65) | L3MBTL1NPC1RAB9AHSD11B1ACKR3 | |
| SCHEMBL8725187 | 0.89 | KMT2A (0.59) | L3MBTL1NPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL13562644 | 0.81 | L3MBTL1 (0.52) | L3MBTL1NPC1RAB9AHSD11B1ACKR3 | |
| SCHEMBL9154155 | 0.81 | L3MBTL1 (0.70) | L3MBTL1NPC1RAB9AHDAC3HDAC1 | |
| SCHEMBL11982908 | 0.80 | TMEM97 (0.67) | L3MBTL1NPC1RAB9AACKR3TMEM97 | |
| SCHEMBL15392066 | 0.79 | TAS2R14 (0.67) | TAS2R14KMT2AMEN1AGER | |
| SCHEMBL28012695 | 0.78 | NPC1 (0.65) | L3MBTL1NPC1RAB9AHSD11B1MAPK1 | |
| SCHEMBL7351073 | 0.77 | HDAC3 (0.44) | TMEM97SIGMAR1KMT2AMAPK1MEN1 | |
| SCHEMBL7346997 | 0.77 | MEN1 (0.42) | L3MBTL1KMT2AMAPK1MEN1HDAC3 | |
| SCHEMBL4485908 | 0.77 | RAB9A (0.69) | L3MBTL1NPC1RAB9AHSD11B1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |