Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 14/20 | 0.47 |
| ▸ | MMP13 | P45452 | 12/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP3 | P08254 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | MMP14 | P50281 | 2/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308395 | 0.84 | MMP1 (0.48) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7304792 | 0.79 | MMP1 (0.60) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7303599 | 0.74 | MMP1 (0.49) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7301981 | 0.73 | MMP1 (0.61) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7300368 | 0.72 | MMP1 (0.40) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7312678 | 0.71 | MMP1 (0.43) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7305971 | 0.71 | MMP1 (0.40) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7302762 | 0.70 | MMP1 (0.81) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7309128 | 0.70 | MMP1 (0.49) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7298907 | 0.68 | MMP1 (0.42) | MMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780386-A1 | Matrix metalloprotease inhibitors | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-25 | — | — | EP | claimed |