Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 3/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 9/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340535 | 0.93 | CACNA1B (0.53) | YAP1CACNA1BACEMMECPA1 | |
| SCHEMBL7341833 | 0.90 | CACNA1B (0.62) | YAP1CACNA1BACEMMECPA1 | |
| SCHEMBL7345947 | 0.88 | CACNA1B (0.49) | YAP1CACNA1BACEMMECPA1 | |
| SCHEMBL7339047 | 0.88 | YAP1 (0.51) | YAP1CACNA1BACEMMECPA1 | |
| SCHEMBL7345873 | 0.86 | YAP1 (0.60) | YAP1CACNA1BACEMMECPA1 | |
| SCHEMBL7345875 | 0.86 | YAP1 (0.60) | YAP1CACNA1BACEMMECPA1 | |
| SCHEMBL7339086 | 0.86 | YAP1 (0.60) | YAP1CACNA1BACEMMECPA1 | |
| SCHEMBL7339092 | 0.86 | YAP1 (0.60) | YAP1CACNA1BACEMMECPA1 | |
| SCHEMBL7347662 | 0.86 | YAP1 (0.55) | YAP1CACNA1BACEMMECPA1 | |
| SCHEMBL7338592 | 0.83 | YAP1 (0.57) | YAP1CACNA1BACEMMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |