Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.33 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.33 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347433 | 1.00 | GRIK1 (0.41) | GRIK1TSHRMMP1MMP2MMP3 | |
| SCHEMBL7278350 | 0.84 | GRIK1 (0.42) | GRIK1TSHRMMP1MMP2MMP3 | |
| SCHEMBL7279080 | 0.84 | GRIK1 (0.42) | GRIK1TSHRMMP1MMP2MMP3 | |
| SCHEMBL7276283 | 0.79 | GRIK1 (0.47) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL7276287 | 0.79 | GRIK1 (0.47) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL11973899 | 0.76 | TSHR (0.39) | TSHRLMNAMAPTHCAR2CYP2D6 | |
| SCHEMBL7285916 | 0.73 | ALDH1A1 (0.49) | MMP9LMNAHCAR2ALDH1A1TDP1 | |
| SCHEMBL7285911 | 0.73 | ALDH1A1 (0.49) | MMP9LMNAHCAR2ALDH1A1TDP1 | |
| SCHEMBL7284141 | 0.73 | GRIK1 (0.42) | GRIK1GRIK2LMNAMAPTGRIA2 | |
| SCHEMBL7284138 | 0.73 | GRIK1 (0.42) | GRIK1GRIK2LMNAMAPTGRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579648-A1 | THIOL-CARBOXYLIC ACID DERIVATIVES AS COLLAGENASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992017444-A1 | THIOL-CARBOXYLIC ACID DERIVATIVES AS COLLAGENASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1992-10-15 | — | — | WO | disclosed |