Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 0.55 |
| ▸ | MMP13 | P45452 | 10/20 | 0.46 |
| ▸ | MMP2 | P08253 | 5/20 | 0.46 |
| ▸ | MMP9 | P14780 | 5/20 | 0.46 |
| ▸ | MMP3 | P08254 | 4/20 | 0.46 |
| ▸ | MMP8 | P22894 | 4/20 | 0.46 |
| ▸ | MMP14 | P50281 | 4/20 | 0.46 |
| ▸ | MMP7 | P09237 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | MMP10 | P09238 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 4/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809651 | 0.91 | MMP1 (0.68) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL7352297 | 0.90 | MMP1 (0.68) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL7352211 | 0.88 | MMP1 (0.45) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL6873149 | 0.82 | MMP1 (0.70) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL14302914 | 0.81 | MMP1 (0.66) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL6818064 | 0.81 | MMP1 (0.78) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL6695057 | 0.81 | MMP1 (0.81) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL3987272 | 0.81 | MMP1 (0.68) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL26434 | 0.81 | MMP1 (0.83) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL6813516 | 0.80 | MMP1 (0.54) | MMP1MMP13MMP2MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0895988-B1 | Arylsulfonylamino hydroxamic acid derivatives | PFIZER PROD INC (US) | 2002-05-22 | — | — | EP | disclosed |
| US-6107337-A | ANTIARTHRITIC AGENTS; ANTICARCINOGENIC AGENTS | PFIZER INC. (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0895988-A1 | Arylsulfonylamino hydroxamic acid derivatives | Pfizer Products Inc. (US) | 1999-02-10 | — | — | EP | disclosed |