Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 12/20 | 0.68 |
| ▸ | MMP13 | P45452 | 13/20 | 0.54 |
| ▸ | MMP2 | P08253 | 5/20 | 0.44 |
| ▸ | MMP8 | P22894 | 4/20 | 0.44 |
| ▸ | MMP3 | P08254 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | MMP14 | P50281 | 2/20 | 0.44 |
| ▸ | MMP12 | P39900 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26434 | 0.91 | MMP1 (0.83) | MMP1MMP13MMP2MMP8MMP3 | |
| SCHEMBL4783958 | 0.90 | MMP1 (0.79) | MMP1MMP13MMP2MMP8MMP3 | |
| SCHEMBL7347598 | 0.90 | MMP1 (0.55) | MMP1MMP13MMP2MMP8MMP3 | |
| SCHEMBL7347709 | 0.88 | MMP1 (0.56) | MMP1MMP13MMP2MMP8MMP3 | |
| SCHEMBL7348159 | 0.85 | MMP1 (0.51) | MMP1MMP13MMP2MMP8MMP3 | |
| SCHEMBL7344996 | 0.84 | MMP1 (0.58) | MMP1MMP13MMP2MMP8MMP9 | |
| SCHEMBL6873149 | 0.82 | MMP1 (0.70) | MMP1MMP13MMP2MMP8MMP3 | |
| SCHEMBL14302914 | 0.81 | MMP1 (0.66) | MMP1MMP13MMP2MMP8MMP3 | |
| SCHEMBL25130 | 0.81 | MMP1 (0.96) | MMP1MMP13MMP2MMP8MMP3 | |
| SCHEMBL26986 | 0.81 | MMP1 (1.00) | MMP1MMP13MMP2MMP8MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0895988-B1 | Arylsulfonylamino hydroxamic acid derivatives | PFIZER PROD INC (US) | 2002-05-22 | — | — | EP | disclosed |
| US-6107337-A | ANTIARTHRITIC AGENTS; ANTICARCINOGENIC AGENTS | PFIZER INC. (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0895988-A1 | Arylsulfonylamino hydroxamic acid derivatives | Pfizer Products Inc. (US) | 1999-02-10 | — | — | EP | disclosed |