Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.50 |
| ▸ | PDE9A | O76083 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413505 | 0.89 | NPSR1 (0.44) | PDE5APDE9ANPSR1MEN1KMT2A | |
| SCHEMBL7351886 | 0.79 | PDE5A (0.50) | PDE5APDE9ANPSR1MEN1KMT2A | |
| SCHEMBL8142801 | 0.77 | CA12 (0.55) | NPSR1MEN1KMT2ACYP1A2NFKB1 | |
| SCHEMBL7347889 | 0.76 | PARP1 (0.39) | NPSR1MEN1KMT2ARXFP1 | |
| SCHEMBL7353145 | 0.75 | NPSR1 (0.72) | NPSR1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL7353512 | 0.75 | GRIA1 (0.50) | NPSR1MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL10745368 | 0.75 | CYP1A2 (0.40) | NPSR1MEN1KMT2ACYP1A2NFKB1 | |
| SCHEMBL8557784 | 0.74 | PDE5A (0.47) | PDE5APDE9ANPSR1MEN1KMT2A | |
| SCHEMBL7351758 | 0.74 | MEN1 (0.36) | NPSR1MEN1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL8910786 | 0.73 | DAO (0.49) | NPSR1MEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633885-A1 | TRIAZOLOQUINOXALIN-1,4-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993006103-A1 | TRIAZOLOQUINOXALIN-1,4-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-04-01 | — | — | WO | disclosed |