Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418199 | 0.82 | DAO (0.49) | DAONPSR1RXFP1ADORA3GABRP | |
| SCHEMBL7413505 | 0.82 | NPSR1 (0.44) | NPSR1RXFP1KDM4EMEN1KMT2A | |
| SCHEMBL7353145 | 0.78 | NPSR1 (0.72) | NPSR1RXFP1KDM4EADORA3MEN1 | |
| SCHEMBL8136188 | 0.75 | FEN1 (0.51) | DAOKDM4EFEN1MEN1KMT2A | |
| SCHEMBL8912201 | 0.74 | PGR (0.45) | NPSR1RXFP1PDE3BPDE3APGR | |
| SCHEMBL7351886 | 0.73 | PDE5A (0.50) | NPSR1RXFP1ADORA3MEN1KMT2A | |
| SCHEMBL7347754 | 0.73 | PDE5A (0.50) | NPSR1RXFP1MEN1KMT2A | |
| SCHEMBL8911220 | 0.73 | GRIN2D (0.42) | GRIA1 | |
| SCHEMBL8134451 | 0.72 | FEN1 (0.51) | DAOKDM4EGABRPGABRDGABRA1 | |
| SCHEMBL7347889 | 0.71 | PARP1 (0.39) | NPSR1RXFP1GRIA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0698024-B1 | [1,2,4]TRIAZOLO [4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1997-01-22 | — | — | EP | disclosed |
| US-5532236-A | TREATMENT OF PARKINSON'S DISEASE | NOVO NORDISK A/S (DK) | 1996-07-02 | — | — | US | disclosed |
| EP-0698024-A1 | 1,2,4]TRIAZOLO 4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994026746-A1 | [1,2,4]TRIAZOLO[4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1994-11-24 | — | — | WO | disclosed |