Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | G6PD | P11413 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910786 | 0.78 | DAO (0.49) | NPSR1RXFP1KDM4EADORA3MEN1 | |
| SCHEMBL7418199 | 0.78 | DAO (0.49) | NPSR1RXFP1ADORA3ADORA2AADORA1 | |
| SCHEMBL7351886 | 0.78 | PDE5A (0.50) | NPSR1RXFP1ADORA3MEN1KMT2A | |
| SCHEMBL7347754 | 0.75 | PDE5A (0.50) | NPSR1RXFP1ALDH1A1MAPTMEN1 | |
| SCHEMBL7413505 | 0.75 | NPSR1 (0.44) | NPSR1RXFP1KDM4EALDH1A1MAPT | |
| SCHEMBL7353512 | 0.74 | GRIA1 (0.50) | NPSR1RXFP1ALDH1A1MAPTADORA3 | |
| SCHEMBL22045238 | 0.73 | NPSR1 (0.55) | NPSR1RXFP1POLBKDM4EALDH1A1 | |
| SCHEMBL14361375 | 0.72 | POLB (0.68) | NPSR1RXFP1POLBKDM4EALDH1A1 | |
| SCHEMBL8138057 | 0.71 | HAVCR2 (0.49) | NPSR1RXFP1KDM4EALDH1A1HPGD | |
| SCHEMBL29948249 | 0.71 | HAVCR2 (0.49) | NPSR1RXFP1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633885-A1 | TRIAZOLOQUINOXALIN-1,4-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1995-01-18 | — | — | EP | claimed |
| WO-1993006103-A1 | TRIAZOLOQUINOXALIN-1,4-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-04-01 | — | — | WO | claimed |
| US-5504085-A | TREATING ISCHEMIA, ANOXIA, HYPOGLYCEMIA AND HEAD, SPINAL CORD TRAUMA | NOVO NORDISK A/S (DK) | 1996-04-02 | — | — | US | disclosed |
| EP-0633885-A1 | TRIAZOLOQUINOXALIN-1,4-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993006103-A1 | TRIAZOLOQUINOXALIN-1,4-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-04-01 | — | — | WO | disclosed |
| US-4668678-A | ANTIALLERGENS | USV PHARMACEUTICAL CORPORATION (US) | 1987-05-26 | — | — | US | disclosed |
| US-4507300-A | Pyridotriazolopyrazine-diones for treating allergy | USV PHARMACEUTICAL CORPORATION (US) | 1985-03-26 | — | — | US | disclosed |
| US-4400382-A | Thiazoloquinoxalin-1,4-diones for treating allergy | USV PHARMACEUTICAL CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |
| EP-0039920-A2 | Triazaloquinoxalin-1,4-diones | USV PHARMACEUTICAL CORPORATION (US) | 1981-11-18 | — | — | EP | disclosed |