Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414612 | 0.81 | CA12 (0.47) | PARP1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7351758 | 0.79 | MEN1 (0.36) | PARP1NPSR1RXFP1MEN1KMT2A | |
| SCHEMBL8910771 | 0.79 | NOTUM (0.41) | GRIA1GRIA2GRIA3GRIA4MEN1 | |
| SCHEMBL8912056 | 0.77 | GRIA1 (0.48) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8911334 | 0.77 | PDE3B (0.40) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8912871 | 0.77 | NOTUM (0.39) | NPSR1RXFP1GRIA1GRIA2GRIA3 | |
| SCHEMBL8911380 | 0.77 | NOTUM (0.45) | — | |
| SCHEMBL7347754 | 0.76 | PDE5A (0.50) | NPSR1RXFP1MEN1KMT2A | |
| SCHEMBL7413505 | 0.76 | NPSR1 (0.44) | NPSR1RXFP1MEN1KMT2A | |
| SCHEMBL8911468 | 0.76 | GRIA1 (0.42) | GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633885-A1 | TRIAZOLOQUINOXALIN-1,4-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993006103-A1 | TRIAZOLOQUINOXALIN-1,4-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-04-01 | — | — | WO | disclosed |