Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CFTR | P13569 | 5/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347799 | 1.00 | TBXA2R (0.57) | TBXA2RLMNAALDH1A1KDM4EALOX5 | |
| SCHEMBL8951088 | 0.91 | TBXA2R (0.54) | TBXA2RLMNAKMT2AMEN1RAB9A | |
| SCHEMBL7356967 | 0.90 | PKM (0.55) | LMNAALDH1A1KDM4EKMT2AL3MBTL1 | |
| SCHEMBL7356971 | 0.90 | PKM (0.55) | LMNAALDH1A1KDM4EKMT2AL3MBTL1 | |
| SCHEMBL10573467 | 0.88 | TBXA2R (0.69) | TBXA2RLMNAKDM4EKMT2ACFTR | |
| SCHEMBL7352223 | 0.81 | PIN1 (0.53) | TBXA2RLMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL7352228 | 0.81 | PIN1 (0.53) | TBXA2RLMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL27441481 | 0.81 | KMT2A (0.52) | TBXA2RLMNAALDH1A1ALOX5PTGS2 | |
| SCHEMBL29184692 | 0.80 | KMT2A (0.64) | LMNAALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL29129969 | 0.79 | MEN1 (0.47) | TBXA2RALDH1A1ALOX5PTGS2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741804-A | Substituted benzimazoles which inhibit platelet aggrecation | SMITHKLINE BEECHAM CORPORATION (US) | 1998-04-21 | — | — | US | disclosed |
| EP-0672034-A4 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION. | SMITHKLINE BEECHAM CORP (US) | 1996-09-25 | — | — | EP | disclosed |
| EP-0672034-A1 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION | SMITHKLINE BEECHAM CORPORATION (US) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994012478-A1 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION | SMITHKLINE BEECHAM CORPORATION (US) | 1994-06-09 | — | — | WO | disclosed |