Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356967 | 1.00 | PKM (0.55) | PKMCYP19A1PIN1HDAC1HDAC8 | |
| SCHEMBL7352223 | 0.91 | PIN1 (0.53) | PKMPIN1POLBKDM4EALDH1A1 | |
| SCHEMBL7352228 | 0.91 | PIN1 (0.53) | PKMPIN1POLBKDM4EALDH1A1 | |
| SCHEMBL7347799 | 0.90 | TBXA2R (0.57) | PKMHDAC1HDAC8KDM4EALDH1A1 | |
| SCHEMBL7347795 | 0.90 | TBXA2R (0.57) | PKMHDAC1HDAC8KDM4EALDH1A1 | |
| SCHEMBL7358797 | 0.82 | KDM4E (0.59) | PIN1HDAC1HDAC8POLBKDM4E | |
| SCHEMBL29184692 | 0.82 | KMT2A (0.64) | PKMALDH1A1RECQLLMNAKMT2A | |
| SCHEMBL8951088 | 0.81 | TBXA2R (0.54) | PIN1HDAC1POLBIRAK4L3MBTL1 | |
| SCHEMBL10573467 | 0.80 | TBXA2R (0.69) | PIN1POLBKDM4ELMNAKMT2A | |
| SCHEMBL2424564 | 0.77 | LMNA (0.56) | PKMCYP19A1PIN1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741804-A | Substituted benzimazoles which inhibit platelet aggrecation | SMITHKLINE BEECHAM CORPORATION (US) | 1998-04-21 | — | — | US | disclosed |
| WO-1994012478-A1 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION | SMITHKLINE BEECHAM CORPORATION (US) | 1994-06-09 | — | — | WO | disclosed |