Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 2/20 | 0.48 |
| ▸ | TAS2R14 | Q9NYV8 | 6/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 5/20 | 0.43 |
| ▸ | MMP9 | P14780 | 5/20 | 0.43 |
| ▸ | MMP13 | P45452 | 5/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350361 | 0.88 | TAS2R14 (0.45) | BMP1TAS2R14CXCR3PTGESTAS2R8 | |
| SCHEMBL7343316 | 0.86 | MMP1 (0.55) | TAS2R14CXCR3PTGESTAS2R8MMP1 | |
| SCHEMBL7351175 | 0.86 | BMP1 (0.51) | BMP1TAS2R14CXCR3PTGESTAS2R8 | |
| Trifluoroacetic Acid SCHEMBL7350356 | 0.85 | BMP1 (0.49) | BMP1TAS2R14CXCR3PTGESTAS2R8 | |
| SCHEMBL7344272 | 0.85 | BMP1 (0.45) | BMP1TAS2R14CXCR3PTGESTAS2R8 | |
| Hydrochloric Acid SCHEMBL7355030 | 0.80 | PTPN1 (0.47) | BMP1TAS2R14CXCR3PTGESTAS2R8 | |
| SCHEMBL7350800 | 0.79 | BMP1 (0.54) | BMP1TAS2R14CXCR3PTGESTAS2R8 | |
| SCHEMBL7357306 | 0.79 | PTPN1 (0.45) | BMP1TAS2R14CXCR3PTGESTAS2R8 | |
| SCHEMBL7348771 | 0.79 | BMP1 (0.53) | BMP1TAS2R14CXCR3PTGESTAS2R8 | |
| SCHEMBL7349249 | 0.77 | BMP1 (0.52) | BMP1TAS2R14CXCR3PTGESTAS2R8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606046-B1 | Arylsulfonamido-substituted hydroxamic acids | CIBA GEIGY AG (CH) | 1997-10-08 | — | — | EP | disclosed |
| US-5646167-A | ADMINISTERED AS METALLOPROTEINASE INHIBITOR, ANTITUMOR OR ANTICARCINOGENIC AGENT | CIBA-GEIGY CORPORATION (US) | 1997-07-08 | — | — | US | disclosed |
| US-5552419-A | METALLOPROTEINASE INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1996-09-03 | — | — | US | disclosed |
| US-5506242-A | METALLOELASTASE INHIBITOR; TREATS EMPHYSEMA | CIBA-GEIGY CORPORATION (US) | 1996-04-09 | — | — | US | disclosed |
| US-5455258-A | Useful as inhibitors of matrix-degrading metalloproteinase enzymes such as stromelysin and/or collegenase | CIBA-GEIGY CORPORATION (US) | 1995-10-03 | — | — | US | disclosed |
| EP-0606046-A1 | Arylsulfonamido-substituted hydroxamic acids | CIBA-GEIGY AG (CH) | 1994-07-13 | — | — | EP | disclosed |