Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.54 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPR3 | P17342 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348985 | 0.88 | ITGB3 (0.69) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7343715 | 0.88 | ITGB3 (0.42) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7352181 | 0.86 | ITGB3 (0.61) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7345620 | 0.85 | ITGB3 (0.56) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7342244 | 0.84 | ITGB3 (0.62) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7350681 | 0.81 | ITGB3 (0.52) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7456479 | 0.79 | F10 (0.47) | ITGB3ITGAV | |
| SCHEMBL5175122 | 0.78 | ITGB3 (0.57) | ITGB3ITGA2BITGAV | |
| SCHEMBL7407517 | 0.77 | ITGB3 (0.50) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7457575 | 0.77 | F10 (0.47) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907637-A1 | PHENYLALAMINE DERIVATIVES AS INTEGRIN INHIBITORS | MERCK PATENT GmbH (DE) | 1999-04-14 | — | — | EP | disclosed |
| WO-1998000395-A1 | PHENYLALAMINE DERIVATIVES AS INTEGRIN INHIBITORS | MERCK PATENT GMBH (DE) | 1998-01-08 | — | — | WO | disclosed |