Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.56 |
| ▸ | ITGAV | P06756 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352181 | 0.90 | ITGB3 (0.61) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7342244 | 0.88 | ITGB3 (0.62) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7350681 | 0.85 | ITGB3 (0.52) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7348077 | 0.85 | ITGB3 (0.54) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7351394 | 0.84 | MAPT (0.44) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL6873358 | 0.84 | TDP1 (0.46) | ITGB3ITGA2BITGAVLTA4H | |
| SCHEMBL7351843 | 0.82 | ITGB3 (0.43) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7297528 | 0.79 | ITGB3 (0.58) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7464600 | 0.78 | ITGB3 (0.48) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL6286612 | 0.78 | LTA4H (0.47) | ITGB3ITGA2BLTA4HMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907637-A1 | PHENYLALAMINE DERIVATIVES AS INTEGRIN INHIBITORS | MERCK PATENT GmbH (DE) | 1999-04-14 | — | — | EP | disclosed |
| WO-1998000395-A1 | PHENYLALAMINE DERIVATIVES AS INTEGRIN INHIBITORS | MERCK PATENT GMBH (DE) | 1998-01-08 | — | — | WO | disclosed |