Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346492 | 0.92 | SLC6A4 (0.42) | SLC6A4MEN1KMT2AKDM4EDRD4 | |
| SCHEMBL7347171 | 0.86 | SLC6A4 (0.42) | SLC6A4MEN1KMT2AKDM4ELMNA | |
| SCHEMBL7348229 | 0.83 | SLC6A4 (0.43) | SLC6A4MEN1KMT2AKDM4ELMNA | |
| SCHEMBL7345316 | 0.82 | NPC1 (0.34) | SLC6A4NPC1LMNANFKB1RAB9A | |
| SCHEMBL7346888 | 0.81 | NPC1 (0.40) | SLC6A4NPC1LMNANFKB1RAB9A | |
| SCHEMBL7348505 | 0.80 | MEN1 (0.53) | SLC6A4MEN1KMT2AKDM4ELMNA | |
| SCHEMBL7354019 | 0.76 | SLC6A4 (0.42) | SLC6A4MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL7352732 | 0.76 | RAB9A (0.46) | KMT2ANPC1LMNANFKB1RAB9A | |
| SCHEMBL7356312 | 0.74 | ALDH1A1 (0.41) | MEN1KMT2ANPC1LMNANFKB1 | |
| SCHEMBL7351720 | 0.74 | KMT2A (0.41) | SLC6A4MEN1KMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |