Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347171 | 0.90 | SLC6A4 (0.42) | SLC6A4MEN1KMT2ALTA4HEPHX2 | |
| SCHEMBL7346492 | 0.87 | SLC6A4 (0.42) | SLC6A4MEN1KMT2ALTA4HEPHX2 | |
| SCHEMBL7348505 | 0.86 | MEN1 (0.53) | SLC6A4MEN1KMT2ALTA4HEPHX2 | |
| SCHEMBL7348152 | 0.83 | SLC6A4 (0.40) | SLC6A4MEN1KMT2AKDM4ELMNA | |
| SCHEMBL7351618 | 0.81 | SLC1A5 (0.39) | SLC6A4KMT2AALDH1A1HTTPPARG | |
| SCHEMBL7354129 | 0.79 | SLC6A4 (0.36) | SLC6A4MEN1KMT2APPARGPPARA | |
| SCHEMBL7344633 | 0.79 | SLC6A4 (0.36) | SLC6A4PPARGPPARA | |
| SCHEMBL7345491 | 0.76 | MEN1 (0.44) | SLC6A4MEN1KMT2ALTA4HEPHX2 | |
| SCHEMBL7346137 | 0.75 | SLC6A4 (0.39) | SLC6A4LTA4HDRD2 | |
| SCHEMBL7351114 | 0.74 | L3MBTL1 (0.42) | KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |