Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.33 |
| ▸ | ITGAV | P06756 | 4/20 | 0.33 |
| ▸ | MDM4 | O15151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340943 | 0.91 | ITGB1 (0.34) | ITGB3ITGB1ITGA5ITGAVMDM4 | |
| SCHEMBL7348831 | 0.91 | ITGB3 (0.33) | ITGB3ITGB1ITGA5ITGAVMDM4 | |
| SCHEMBL7348225 | 0.88 | ITGB3 (0.38) | ITGB3ITGB1ITGAVGAAITGA2B | |
| SCHEMBL7336943 | 0.82 | NPC1 (0.33) | ITGB3ITGB1ITGA5ITGAVMDM4 | |
| SCHEMBL7347263 | 0.82 | ITGB3 (0.34) | ITGB3ITGB1ITGA5ITGAVMDM4 | |
| SCHEMBL7341076 | 0.81 | SMN1; SMN2 (0.36) | ITGB3ITGAVNPC1RAB9AITGA2B | |
| SCHEMBL7403130 | 0.80 | HTT (0.36) | ITGB3ITGB1ITGA5ITGAVL3MBTL1 | |
| SCHEMBL7341130 | 0.79 | KMT2A (0.35) | ITGB3ITGB1ITGA5ITGAVMDM4 | |
| SCHEMBL7348823 | 0.79 | ITGB3 (0.37) | ITGB3ITGB1ITGA5ITGAVGAA | |
| SCHEMBL7340934 | 0.79 | ITGB3 (0.37) | ITGB3ITGB1ITGA5ITGAVGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1998-07-01 | — | — | EP | claimed |
| WO-1997008145-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-03-06 | — | — | WO | claimed |