Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346162 | 0.87 | HTR1A (0.38) | HTR1ASLC6A3SLC6A4KCNH2DRD2 | |
| SCHEMBL7349099 | 0.87 | HTR1A (0.39) | HTR1ASLC6A3SLC6A4KCNH2DRD2 | |
| SCHEMBL7352340 | 0.83 | HTR1A (0.42) | HTR1ASLC6A3SLC6A4ACHEKCNH2 | |
| SCHEMBL7352557 | 0.80 | HTR1A (0.36) | HTR1ASLC6A3SLC6A4SIGMAR1 | |
| SCHEMBL7350624 | 0.78 | PER2 (0.37) | HTR1A | |
| SCHEMBL7356102 | 0.75 | CYP3A4 (0.37) | SLC6A3SLC6A4 | |
| SCHEMBL7357631 | 0.75 | HTR1A (0.62) | HTR1ASLC6A3SLC6A4ACHEDRD2 | |
| SCHEMBL7352464 | 0.75 | KCNH2 (0.33) | HTR1AKCNH2 | |
| SCHEMBL7357652 | 0.74 | NPSR1 (0.39) | HTR1A | |
| SCHEMBL7352714 | 0.74 | PER2 (0.38) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |