Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7349099 | 0.88 | HTR1A (0.39) | HTR1ADRD2SIGMAR1DRD3LMNA | |
| SCHEMBL7348333 | 0.87 | HTR1A (0.42) | HTR1ADRD2SIGMAR1SLC6A3SLC6A4 | |
| SCHEMBL7347489 | 0.85 | HTR1A (0.38) | HTR1ADRD2SIGMAR1DRD3LMNA | |
| SCHEMBL7354949 | 0.83 | HTR1A (0.34) | HTR1ADRD2SIGMAR1DRD3LMNA | |
| SCHEMBL7346715 | 0.79 | HTR1A (0.54) | HTR1ADRD2SIGMAR1DRD3LMNA | |
| SCHEMBL7349078 | 0.78 | HTR1A (0.35) | HTR1ADRD2SIGMAR1DRD3LMNA | |
| SCHEMBL7346150 | 0.77 | CYP2D6 (0.35) | HTR1ADRD2SLC6A4ADRA1BKCNH2 | |
| SCHEMBL7350499 | 0.73 | DRD2 (0.44) | HTR1ADRD2SIGMAR1DRD3SLC6A3 | |
| SCHEMBL7346136 | 0.72 | HTR1A (0.39) | HTR1ADRD2SIGMAR1DRD3LMNA | |
| SCHEMBL7350624 | 0.72 | PER2 (0.37) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |