Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 9/20 | 0.50 |
| ▸ | METAP2 | P50579 | 5/20 | 0.39 |
| ▸ | METAP1 | P53582 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344258 | 0.90 | REN (0.48) | RENMETAP2METAP1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7343864 | 0.89 | REN (0.47) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL7317650 | 0.84 | REN (0.53) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL7317656 | 0.84 | REN (0.53) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL7291539 | 0.81 | REN (0.53) | RENMETAP2METAP1 | |
| SCHEMBL9177605 | 0.81 | REN (0.53) | RENMETAP2METAP1 | |
| SCHEMBL10433749 | 0.81 | REN (0.53) | RENMETAP2METAP1 | |
| SCHEMBL9858518 | 0.78 | REN (0.56) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL9575386 | 0.78 | REN (0.56) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL9685661 | 0.78 | REN (0.56) | RENMETAP2METAP1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120718-A | Fungicides | ABBOTT LABORATORIES (US) | 1992-06-09 | — | — | US | disclosed |