Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 8/20 | 0.56 |
| ▸ | METAP2 | P50579 | 8/20 | 0.44 |
| ▸ | METAP1 | P53582 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858518 | 1.00 | REN (0.56) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL9685661 | 1.00 | REN (0.56) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL9683843 | 0.86 | REN (0.69) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL9684516 | 0.86 | REN (0.69) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL14420286 | 0.86 | REN (0.53) | RENMETAP2METAP1 | |
| SCHEMBL8826686 | 0.86 | REN (0.56) | RENMETAP2METAP1 | |
| SCHEMBL14415376 | 0.86 | REN (0.53) | RENMETAP2METAP1 | |
| SCHEMBL7317656 | 0.85 | REN (0.53) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL9177605 | 0.85 | REN (0.53) | RENMETAP2METAP1 | |
| SCHEMBL7291539 | 0.85 | REN (0.53) | RENMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258183-B1 | PROCESS FOR THE PREPARATION OF 5-AMINO-4-HYDROXYVALERIC-ACID DERIVATIVES | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |
| EP-0258183-A2 | Process for the preparation of 5-amino-4-hydroxyvaleric-acid derivatives | CIBA-GEIGY AG (CH) | 1988-03-02 | — | — | EP | disclosed |