Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.83 |
| ▸ | MAOA | P21397 | 8/20 | 0.83 |
| ▸ | RXRA | P19793 | 1/20 | 0.58 |
| ▸ | RXRB | P28702 | 1/20 | 0.58 |
| ▸ | RXRG | P48443 | 1/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347439 | 0.87 | MAOB (0.67) | MAOBMAOARXRARXRBRXRG | |
| SCHEMBL560607 | 0.85 | MAOB (0.81) | MAOBMAOA | |
| SCHEMBL27771283 | 0.83 | FADS1 (0.67) | MAOBMAOARXRARXRBRXRG | |
| SCHEMBL1557204 | 0.82 | RXRA (0.65) | MAOBMAOARXRARXRBRXRG | |
| SCHEMBL1557562 | 0.82 | MAOB (0.64) | MAOBMAOARXRARXRBRXRG | |
| SCHEMBL7351953 | 0.81 | MAPT (0.84) | MAOBMAOANR4A2 | |
| SCHEMBL9908790 | 0.81 | MAOB (0.65) | MAOBMAOARXRARXRBRXRG | |
| SCHEMBL17848436 | 0.81 | MAOB (0.61) | MAOBMAOA | |
| SCHEMBL8694329 | 0.80 | MAOB (1.00) | MAOBMAOARXRARXRBRXRG | |
| SCHEMBL1557166 | 0.80 | MAOB (0.60) | MAOBMAOARXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380755-A | Monoamine oxidase inhibitors | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-01-10 | — | — | US | disclosed |