Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | AGXT | P21549 | 2/20 | 0.34 |
| ▸ | EPOR | P19235 | 3/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | SOD1 | P00441 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348493 | 1.00 | PPARA (0.38) | PPARAPPARGCHRM2CHRM1CHRM3 | |
| SCHEMBL7348497 | 0.81 | CHRM2 (0.40) | PPARAPPARGCHRM2CHRM1CHRM3 | |
| SCHEMBL7296934 | 0.81 | CHRM2 (0.48) | PPARACHRM2CHRM1CHRM3SOD1 | |
| SCHEMBL7296937 | 0.81 | CHRM2 (0.48) | PPARACHRM2CHRM1CHRM3SOD1 | |
| SCHEMBL6201718 | 0.80 | PPARA (0.37) | PPARAPPARGCHRM2CHRM1CHRM3 | |
| SCHEMBL9167101 | 0.78 | KMT2A (0.46) | PPARASOD1 | |
| SCHEMBL9167096 | 0.78 | KMT2A (0.46) | PPARASOD1 | |
| SCHEMBL8638304 | 0.76 | ALDH1A1 (0.42) | PPARAPPARGCHRM2CHRM1CHRM3 | |
| SCHEMBL8048535 | 0.74 | CHRM2 (0.43) | PPARAPPARGCHRM2CHRM1CHRM3 | |
| SCHEMBL7341715 | 0.74 | RELA (0.40) | CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4514401-A | CARDIOTONICS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-04-30 | — | — | US | disclosed |
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |