Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 11/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 9/20 | 0.39 |
| ▸ | P2RY4 | P51582 | 8/20 | 0.39 |
| ▸ | TYMP | P19971 | 3/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20527120 | 0.83 | TYMP (0.41) | POLBP2RY6P2RY2P2RY4TYMP | |
| SCHEMBL3574271 | 0.80 | DUT (0.49) | TYMP | |
| SCHEMBL29703059 | 0.78 | POLB (0.44) | POLBP2RY6P2RY2P2RY4TYMP | |
| SCHEMBL30165345 | 0.77 | POLB (0.54) | POLBP2RY6P2RY2P2RY4TYMP | |
| SCHEMBL6312752 | 0.77 | DUT (0.45) | TYMP | |
| SCHEMBL7776576 | 0.77 | DUT (0.45) | TYMP | |
| SCHEMBL27125397 | 0.77 | DUT (0.45) | TYMP | |
| SCHEMBL22984003 | 0.77 | TYMP (0.40) | POLBTYMP | |
| SCHEMBL21545803 | 0.77 | POLB (0.50) | POLBP2RY6P2RY2P2RY4NT5E | |
| SCHEMBL733367 | 0.76 | TYMP (0.47) | TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138330-B2 | Solid phase synthesis via deblocking immobilized nucleoside, then coupling acyl protected nucleoside phosphoramidite | SIGMA-ALDRICH CO. LLC (US) | 2012-03-20 | — | — | US | disclosed |