Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.72 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.72 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.48 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7387468 | 0.88 | ITGB3 (0.84) | ITGB3ITGA2BPLA2G2AF10 | |
| SCHEMBL7381387 | 0.88 | ITGB3 (0.84) | ITGB3ITGA2BPLA2G2AF10 | |
| SCHEMBL7357410 | 0.86 | ITGB3 (0.68) | ITGB3ITGA2BPLA2G2AF10 | |
| SCHEMBL7348662 | 0.84 | ITGB3 (0.50) | ITGB3ITGA2BPLA2G2A | |
| SCHEMBL7381799 | 0.84 | ITGB3 (1.00) | ITGB3ITGA2BPLA2G2A | |
| SCHEMBL7348953 | 0.82 | ITGB3 (0.73) | ITGB3ITGA2BPLA2G2A | |
| SCHEMBL7349392 | 0.80 | ITGB3 (0.71) | ITGB3ITGA2BPLA2G2AF10 | |
| SCHEMBL7389600 | 0.80 | ITGB3 (0.76) | ITGB3ITGA2BPLA2G2A | |
| SCHEMBL7350092 | 0.79 | ITGB3 (0.69) | ITGB3ITGA2BPLA2G2AF10 | |
| SCHEMBL7350222 | 0.79 | ITGB3 (0.74) | ITGB3ITGA2BPLA2G2AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543425-A | ANTIAGGLOMERANTS | G. D. SEARLE & CO. (US) | 1996-08-06 | — | — | US | claimed |
| US-5409939-A | Phenyl amidine thio derivatives useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-04-25 | — | — | US | claimed |
| WO-1994018162-A1 | PHENYL AMIDINE THIO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-18 | — | — | WO | claimed |
| US-5543425-A | ANTIAGGLOMERANTS | G. D. SEARLE & CO. (US) | 1996-08-06 | — | — | US | disclosed |
| US-5409939-A | Phenyl amidine thio derivatives useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-04-25 | — | — | US | disclosed |
| WO-1994018162-A1 | PHENYL AMIDINE THIO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-18 | — | — | WO | disclosed |