Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357417 | 0.87 | ITGB3 (0.46) | ITGB3ITGA2BPLA2G2ACTSGCMA1 | |
| SCHEMBL7381804 | 0.85 | ITGB3 (0.67) | ITGB3ITGA2BPLA2G2ACTSGCMA1 | |
| SCHEMBL7348653 | 0.84 | ITGB3 (0.72) | ITGB3ITGA2BPLA2G2A | |
| SCHEMBL7348963 | 0.82 | ITGB3 (0.50) | ITGB3ITGA2BPLA2G2ACTSGCMA1 | |
| SCHEMBL7349409 | 0.82 | ITGB3 (0.48) | ITGB3ITGA2BPLA2G2ACTSGCMA1 | |
| SCHEMBL7389607 | 0.81 | ITGB3 (0.50) | ITGB3ITGA2BPLA2G2ACTSGCMA1 | |
| SCHEMBL7350097 | 0.81 | ITGB3 (0.46) | ITGB3ITGA2BPLA2G2ACTSGCMA1 | |
| SCHEMBL7350231 | 0.80 | PLA2G2A (0.68) | ITGB3ITGA2BPLA2G2ACTSGCMA1 | |
| SCHEMBL7378676 | 0.79 | ITGB3 (0.49) | ITGB3ITGA2BPLA2G2AKMT2ACTSG | |
| SCHEMBL7350495 | 0.79 | ITGB3 (0.45) | ITGB3ITGA2BPLA2G2ACTSGCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994018162-A1 | PHENYL AMIDINE THIO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-18 | — | — | WO | claimed |
| WO-1994018162-A1 | PHENYL AMIDINE THIO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-18 | — | — | WO | disclosed |