Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ILK | Q13418 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | DBH | P09172 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14612616 | 0.85 | KMT2A (0.37) | KMT2ACYP1A2CYP2D6MEN1SMN1; SMN2 | |
| SCHEMBL15054521 | 0.83 | MAPT (0.43) | KMT2ACYP1A2CYP2D6MEN1SMN1; SMN2 | |
| SCHEMBL1942011 | 0.82 | ALDH1A1 (0.35) | KMT2ACYP1A2MEN1MAPTGAA | |
| SCHEMBL8467047 | 0.81 | PDGFRB (0.37) | MAPTILKPTGS2DBH | |
| SCHEMBL4830230 | 0.80 | GAA (0.54) | KMT2ACYP1A2CYP2D6MEN1SMN1; SMN2 | |
| SCHEMBL19088270 | 0.75 | KMT2A (0.41) | KMT2ACYP1A2CYP2D6MEN1SMN1; SMN2 | |
| SCHEMBL19120435 | 0.74 | SCN4A (0.38) | SMN1; SMN2MAPTILKPTGS2 | |
| SCHEMBL31574688 | 0.72 | MEP1B (0.39) | CYP1A2SMN1; SMN2MAPTALDH1A1GFER | |
| SCHEMBL15561614 | 0.72 | CA2 (0.43) | KMT2AMEN1SMN1; SMN2MAPTLMNA | |
| SCHEMBL29582345 | 0.72 | CA2 (0.43) | KMT2AMEN1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4207327-A | N-(4-Pyrazolidinyl)benzamides and their amino precursors | A. H. ROBINS COMPANY, INC. (US) | 1980-06-10 | — | — | US | disclosed |