Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 6/20 | 0.57 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | XIAP | P98170 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7349516 | 1.00 | TPH1 (0.57) | TPH1PDCD1CD274SLC7A5PTGS1 | |
| SCHEMBL7229409 | 0.90 | ALDH1A1 (0.55) | TPH1LDHAROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL7229407 | 0.88 | ALDH1A1 (0.57) | TPH1LDHAROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL28745095 | 0.86 | ROCK2 (0.50) | TPH1PDCD1CD274LDHAGRIA2 | |
| SCHEMBL18554064 | 0.85 | ROCK2 (0.52) | TPH1ROCK2ROCK1 | |
| SCHEMBL20474581 | 0.85 | ROCK2 (0.52) | TPH1ROCK2ROCK1 | |
| Phenylalanine SCHEMBL1703069 | 0.85 | PPARG (0.63) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL7227938 | 0.85 | PPARG (0.63) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL31398354 | 0.85 | PPARG (0.63) | TPH1SLC7A5PTGS1ALPIPKM | |
| Dl-Phenylalanine SCHEMBL28033224 | 0.85 | PPARG (0.63) | TPH1SLC7A5PTGS1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |