Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347553 | 0.85 | KDM4E (0.59) | KDM4EPOLBTDP1ALDH1A1MAPT | |
| SCHEMBL10373798 | 0.83 | KDM4E (0.60) | KDM4EPOLBTDP1ADORA2BALDH1A1 | |
| SCHEMBL7341261 | 0.82 | KDM4E (0.67) | KDM4EPOLBTDP1ADORA2BALDH1A1 | |
| SCHEMBL27395888 | 0.82 | KDM4E (0.84) | KDM4EPOLBTDP1ADORA2BALDH1A1 | |
| SCHEMBL7347855 | 0.82 | MAPT (0.51) | KDM4EPOLBTDP1ALDH1A1MAPT | |
| SCHEMBL7348023 | 0.81 | CACNA1C (0.48) | KDM4ETDP1ALDH1A1MAPTNPSR1 | |
| SCHEMBL7349519 | 0.81 | ADORA3 (0.57) | KDM4EPOLBALDH1A1MAPTNPSR1 | |
| SCHEMBL7340139 | 0.81 | ADORA3 (0.47) | KDM4ETDP1ALDH1A1MAPTADORA3 | |
| SCHEMBL7342397 | 0.81 | ADORA3 (0.47) | KDM4ETDP1ALDH1A1MAPTADORA3 | |
| SCHEMBL7343547 | 0.81 | ADORA3 (0.47) | KDM4ETDP1ALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4833150-A | HYPOTENSIVES, ANTIARRHYTHMIA AGENTS | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1989-05-23 | — | — | US | disclosed |
| US-4652573-A | HYPOTENSIVE AGENTS | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0194685-A1 | 1,4-Dihydropyridines | Whitby Research Incorporated (US) | 1986-09-17 | — | — | EP | disclosed |