Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7349928 | 1.00 | CAPN1 (0.61) | CAPN1LMNAPOLBMAPTTHRB | |
| SCHEMBL7312803 | 0.93 | CAPN1 (0.53) | CAPN1LMNAPOLBMAPTTHRB | |
| SCHEMBL7312816 | 0.93 | CAPN1 (0.53) | CAPN1LMNAPOLBMAPTTHRB | |
| SCHEMBL7348921 | 0.88 | RAB9A (0.53) | CAPN1LMNAPOLBMAPTTHRB | |
| SCHEMBL7305250 | 0.82 | TAS1R3 (0.52) | CAPN1LMNATHRBMEN1NPC1 | |
| SCHEMBL8885687 | 0.81 | CAPN1 (0.42) | CAPN1LMNAPOLBMAPTTHRB | |
| SCHEMBL8885698 | 0.81 | CAPN1 (0.42) | CAPN1LMNAPOLBMAPTTHRB | |
| SCHEMBL7342545 | 0.79 | PSMB5 (0.47) | POLBMAPTNPC1RAB9AKMT2A | |
| SCHEMBL7342540 | 0.79 | PSMB5 (0.47) | POLBMAPTNPC1RAB9AKMT2A | |
| SCHEMBL7343844 | 0.79 | HPGD (0.53) | POLBMAPTMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603873-B1 | Aminoketone derivatives | MITSUBISHI CHEM CORP (JP) | 1998-04-15 | — | — | EP | disclosed |
| US-5424325-A | Inibitors of thiol protease and may be used as therapeutic agents for treating muscular dystrophy, cataracts, strokes | MITSUBISHI KASEI CORPORATION (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0603873-A1 | Aminoketone derivatives | Mitsubishi Chemical Corporation (JP) | 1994-06-29 | — | — | EP | disclosed |