Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301793 | 0.92 | MAPT (0.70) | MAPTKDM4EGAAALDH1A1POLB | |
| SCHEMBL9755054 | 0.90 | MAPT (0.65) | MAPTKDM4EGAAALDH1A1POLB | |
| SCHEMBL37830 | 0.89 | MAPT (0.63) | MAPTKDM4EGAAALDH1A1POLB | |
| SCHEMBL4295085 | 0.89 | MAPT (0.63) | MAPTKDM4EGAAALDH1A1POLB | |
| SCHEMBL29928397 | 0.89 | MAPT (0.63) | MAPTKDM4EGAAALDH1A1POLB | |
| SCHEMBL30670380 | 0.87 | MAPT (0.58) | MAPTKDM4EGAAALDH1A1POLB | |
| SCHEMBL13248200 | 0.87 | MAPT (0.58) | MAPTKDM4EGAAALDH1A1POLB | |
| SCHEMBL8107611 | 0.86 | MAPT (0.60) | MAPTKDM4EALDH1A1POLBKMT2A | |
| SCHEMBL4427988 | 0.86 | MAPT (0.57) | MAPTKDM4EGAAALDH1A1POLB | |
| SCHEMBL31481345 | 0.86 | MAPT (0.57) | MAPTKDM4EGAAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63238026-A | — | — | None | — | — | JP | disclosed |
| US-6288065-B1 | CENTRAL NERVOUS SYSTEM DISORDERS; PARKINSON*S AND ALZHEIMER*S DISEASE | SCHERING AKTIENGESEELLSCHAFT (DE) | 2001-09-11 | — | — | US | disclosed |
| US-6057304-A | Quinoxaline-phosphonic acid derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |
| EP-0572217-B1 | Rapid, improved immunoassays via the use of novel immune complex transfer techniques | CIBA CORNING DIAGNOSTICS CORP (US) | 1999-07-28 | — | — | EP | disclosed |
| CN-1038840-C | para-dinitrogen naphthalene derivative, its preparation method and its medical use | SCHERING AG (DE) | 1998-06-24 | — | — | CN | disclosed |
| US-5622825-A | REACTING MIXED ANHYDRIDE INTERMEDIATE WITH NUCLEOPHILIC GROUP CONTAINING POLYNUCLEOTIDE | CIBA CORNING DIAGNOSTICS CORP. (US) | 1997-04-22 | — | — | US | disclosed |
| EP-0537994-B1 | Efficient gene probe conjugations by an unconventional mixed anhydride method | CIBA CORNING DIAGNOSTICS CORP (US) | 1996-04-10 | — | — | EP | disclosed |
| EP-0444158-B1 | CONJUGATED POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | UNIV CALIFORNIA (US) | 1996-01-03 | — | — | EP | disclosed |
| US-5314817-A | Hapten modified with pyrimidine dimer or benzylammonium group, useful in reactions of proteins, nucleic acids and carbohydrates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-05-24 | — | — | US | disclosed |
| US-5312730-A | Rapid sensitive binding assay including forming complex of labeled specific binder, analyte, specific binder, lipophilic material, first solid phase; use of detergents or enzymes to separate binder-analyte-binder complex from solid phase | CIBA CORNING DIAGNOSTICS CORP. (US) | 1994-05-17 | — | — | US | disclosed |
| EP-0444158-A4 | CONJUGATED POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | — | 1992-06-24 | — | — | EP | disclosed |
| EP-0445214-A4 | CATALYTIC AND REACTIVE POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | — | 1991-11-13 | — | — | EP | disclosed |
| EP-0445214-A1 | CATALYTIC AND REACTIVE ANTIBODIES AND ANTIBODY FRAGMENTS AND METHODS FOR THEIR PREPARATION AND USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-09-11 | — | — | EP | disclosed |
| EP-0444158-A1 | CONJUGATED POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE. | UNIV CALIFORNIA (US) | 1991-09-04 | — | — | EP | disclosed |
| WO-1990005749-A1 | CONJUGATED POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1990-05-31 | — | — | WO | disclosed |
| WO-1990005746-A1 | CATALYTIC AND REACTIVE POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1990-05-31 | — | — | WO | disclosed |
| US-4791055-A | ENZYME-CLEAVABLE BONDS | MILES INC. (US) | 1988-12-13 | — | — | US | disclosed |
| JP-S63238026-A | PURIFICATION OR ORGANIC NONLINEAR OPTICAL MATERIAL BEARING HYDROGEN BONDS | SHARP CORP | 1988-10-04 | — | — | JP | disclosed |
| US-4629688-A | CLINICAL ANALYSIS | MILES LABORATORIES, INC. (US) | 1986-12-16 | — | — | US | disclosed |
| US-4383031-A | LIGANDS; IMMUNOASSAY; SIMPLIFICATION; DIAGNOSIS/MEDICAL/ | MILES LABORATORIES, INC. (US) | 1983-05-10 | — | — | US | disclosed |