Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37830 | 0.99 | MAPT (0.63) | MAPTKDM4EALDH1A1POLBGAA | |
| SCHEMBL4295085 | 0.99 | MAPT (0.63) | MAPTKDM4EALDH1A1POLBGAA | |
| SCHEMBL29928397 | 0.99 | MAPT (0.63) | MAPTKDM4EALDH1A1POLBGAA | |
| SCHEMBL4301793 | 0.96 | MAPT (0.70) | MAPTKDM4EALDH1A1POLBGAA | |
| SCHEMBL7349997 | 0.90 | MAPT (0.62) | MAPTKDM4EALDH1A1POLBGAA | |
| SCHEMBL10932609 | 0.88 | MAPT (0.63) | MAPTKDM4EALDH1A1POLBGAA | |
| SCHEMBL17875231 | 0.87 | MAPT (0.56) | MAPTKDM4EALDH1A1POLBGAA | |
| SCHEMBL8147273 | 0.85 | MAPT (0.65) | MAPTKDM4EALDH1A1POLBHCAR3 | |
| SCHEMBL27343040 | 0.85 | MAPT (0.73) | MAPTKDM4EALDH1A1POLBGAA | |
| SCHEMBL8536167 | 0.84 | PRSS1 (0.56) | MAPTKDM4EALDH1A1POLBHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005605-A1 | CYCLODEXTRIN LABELS FOR IMMUNOASSAY AND BIOCHEMICAL ANALYSIS | KOSAK KENNETH M (US) | 1991-05-02 | — | — | WO | disclosed |