Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410862 | 0.85 | TDP1 (0.63) | TDP1LMNAALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL7405175 | 0.81 | ALDH1A1 (0.65) | TDP1LMNAALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL13685906 | 0.77 | TDP1 (0.69) | TDP1LMNAALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL3866555 | 0.76 | TDP1 (0.68) | TDP1LMNAALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL10544073 | 0.75 | LMNA (0.66) | TDP1LMNAALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL13685905 | 0.75 | TDP1 (0.66) | TDP1LMNAALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL7340865 | 0.75 | USP2 (0.37) | TDP1LMNAHSD17B10USP2 | |
| Penflutizide SCHEMBL49138 | 0.72 | LMNA (0.65) | TDP1LMNAALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL13685873 | 0.72 | TDP1 (0.62) | TDP1LMNAALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL11038368 | 0.72 | TDP1 (0.77) | TDP1LMNAALDH1A1CYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4634689-A | HYPOTENSIVE AGENTS | SCHERING CORPORATION (US) | 1987-01-06 | — | — | US | disclosed |