Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410862 | 0.82 | TDP1 (0.63) | ALDH1A1CYP1A2L3MBTL1TDP1LMNA | |
| SCHEMBL7350074 | 0.81 | TDP1 (0.62) | ALDH1A1CYP1A2L3MBTL1TDP1LMNA | |
| SCHEMBL18309810 | 0.79 | ALDH1A1 (0.80) | ALDH1A1CYP1A2L3MBTL1TDP1LMNA | |
| Benzylhydrochlorothiazide SCHEMBL18314134 | 0.79 | ALDH1A1 (1.00) | ALDH1A1CYP1A2L3MBTL1TDP1LMNA | |
| Benzylhydrochlorothiazide SCHEMBL49671 | 0.79 | ALDH1A1 (1.00) | ALDH1A1CYP1A2L3MBTL1TDP1LMNA | |
| Hydrobentizide SCHEMBL564232 | 0.74 | ALDH1A1 (0.76) | ALDH1A1CYP1A2L3MBTL1TDP1LMNA | |
| SCHEMBL14140882 | 0.72 | TDP1 (0.60) | ALDH1A1CYP1A2L3MBTL1TDP1LMNA | |
| SCHEMBL13685990 | 0.71 | TDP1 (0.58) | ALDH1A1CYP1A2L3MBTL1TDP1LMNA | |
| SCHEMBL13685906 | 0.70 | TDP1 (0.69) | ALDH1A1CYP1A2L3MBTL1TDP1LMNA | |
| SCHEMBL11038368 | 0.69 | TDP1 (0.77) | ALDH1A1CYP1A2L3MBTL1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015641-A | Dipeptide for vision defects | ANDREWS DAVID R (US) | 1991-05-14 | — | — | US | disclosed |
| US-4885293-A | CARBOXYALKYL DIPEPTIDES | SCHERING CORPORATION (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0195817-B1 | CARBOXYALKYLDIPEPTIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1989-10-18 | — | — | EP | disclosed |
| US-4826816-A | Antihypertensive compounds | SCHERING CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| US-4634698-A | TOPICAL HYPOTENSIVES | SCHERING CORPORATION (US) | 1987-01-06 | — | — | US | disclosed |
| EP-0195817-A1 | CARBOXYALKYLDIPEPTIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | SCHERING CORP (US) | 1986-10-01 | — | — | EP | disclosed |
| WO-1986001803-A1 | CARBOXYALKYLDIPEPTIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1986-03-27 | — | — | WO | disclosed |
| US-4556655-A | TREATMENT OF CARDIOVASCULAR DISORDERS AND GLAUCOMA | SCHERING CORPORATION (US) | 1985-12-03 | — | — | US | disclosed |