Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.64 |
| ▸ | HTR3A | P46098 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | APEX1 | P27695 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.57 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.53 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL295194 | 1.00 | TAAR1 (0.64) | TAAR1NFKB1HTR3ATSHRHIF1A | |
| SCHEMBL1239403 | 1.00 | TAAR1 (0.64) | TAAR1NFKB1HTR3ATSHRHIF1A | |
| Hydrochloric Acid SCHEMBL3403721 | 0.98 | APEX1 (0.65) | TAAR1NFKB1HTR3ATSHRHIF1A | |
| Hydrochloric Acid SCHEMBL19666947 | 0.98 | APEX1 (0.65) | TAAR1NFKB1HTR3ATSHRHIF1A | |
| Hydrochloric Acid SCHEMBL19666945 | 0.98 | APEX1 (0.65) | TAAR1NFKB1HTR3ATSHRHIF1A | |
| SCHEMBL4074768 | 0.87 | TAAR1 (0.80) | TAAR1NFKB1HTR3ATSHRHIF1A | |
| SCHEMBL8350845 | 0.82 | AOC3 (0.53) | TAAR1NFKB1HTR3ATSHRHIF1A | |
| SCHEMBL7350168 | 0.82 | AOC3 (0.53) | TAAR1NFKB1HTR3ATSHRHIF1A | |
| SCHEMBL8355999 | 0.82 | AOC3 (0.53) | TAAR1NFKB1HTR3ATSHRHIF1A | |
| SCHEMBL15607723 | 0.80 | AOC3 (0.52) | TAAR1NFKB1HTR3ATSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100143322-A1 | USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE | PLT PATENT & LICENCE TRADING LTD., C/O THE B-NET (GB) | 2010-06-10 | — | — | US | claimed |
| US-20260138987-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | CONTINEUM THERAPEUTICS INC (US) | 2026-05-21 | — | — | US | disclosed |
| US-12565501-B2 | Muscarinic acetylcholine M1 receptor antagonists | CONTINEUM THERAPEUTICS, INC. (US) | 2026-03-03 | — | — | US | disclosed |
| US-20250243208-A1 | BICYCLIC HETEROCYCLES AS MRGPRX2 ANTAGONISTS | INCYTE CORPORATION | 2025-07-31 | — | — | US | disclosed |
| US-20250171455-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | CONTINEUM THERAPEUTICS INC (US) | 2025-05-29 | — | — | US | disclosed |
| CN-119954828-A | Parallel ring compound and preparation and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-116322699-B | Parallel ring compound and preparation and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2025-02-11 | — | — | CN | disclosed |
| US-20240294545-A1 | A CLASS OF FUSED RING COMPOUNDS, AND PREPARATION AND USE THEREOF | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD (CN) | 2024-09-05 | — | — | US | disclosed |
| US-20240124408-A1 | Substituted Cyclohexanecarboxamides, Their Preparation and Their Therapeutic Application | SANOFI (FR) | 2024-04-18 | — | — | US | disclosed |
| EP-4219499-A1 | A CLASS OF FUSED RING COMPOUNDS, AND PREPARATION AND USE THEREOF | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |
| US-4783457-A | NON-FORMAMIDINE OCTOPAMINE AGONIST | THE GENERAL HOSPITAL CORPORATION (US) | 1988-11-08 | — | — | US | disclosed |
| US-4678775-A | P-OCTOPAMINE AGONIST, STIMULATOR OF ADENYLATE CYCLASE, ANALOG OF CYCLIC ADENOSINE MONOPHOSPHATE | GENERAL HOSPITAL CORPORATION THE | 1987-07-07 | — | — | US | disclosed |
| US-4643849-A | ANTIULCER, ANTISECRETORY AGENTS | TOYAMA CHEMICAL CO., LTD. (JP) | 1987-02-17 | — | — | US | disclosed |
| EP-0179881-A1 | PEST CONTROLLING AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 1986-05-07 | — | — | EP | disclosed |
| WO-1985005038-A1 | PEST CONTROLLING AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 1985-11-21 | — | — | WO | disclosed |
| EP-0060954-B1 | DERIVATIVES OF FLUOROPHENACYL AMINES AND THEIR THERAPEUTIC USE | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1984-08-15 | — | — | EP | disclosed |
| EP-0060954-A1 | Derivatives of fluorophenacyl amines and their therapeutic use | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1982-09-29 | — | — | EP | disclosed |
| US-4010191-A | Acyl derivatives of substituted bis-arylalkylamino compounds | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1977-03-01 | — | — | US | disclosed |
| US-3983133-A | CNS ANTIDEPRESSANTS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-09-28 | — | — | US | disclosed |
| US-3963718-A | CENTRAL NERVOUS SYSTEM ANTIDEPRESSANTS | JANSSEN PHARMACEUTICA (BE) | 1976-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294545-A1 | A CLASS OF FUSED RING COMPOUNDS, AND PREPARATION AND USE THEREOF | ATM, CHEK2, CHEK1 | TAAR1 3695/4885NFKB1 361/4885HTR3A 4013/4885 |
| US-12565501-B2 | Muscarinic acetylcholine M1 receptor antagonists | CHRM1, CHRM2, CHRM3 | TAAR1 31/4885NFKB1 4703/4885HTR3A 102/4885 |
| US-20240124408-A1 | Substituted Cyclohexanecarboxamides, Their Preparation and Their Therapeutic Application | TRPM8, TAS2R8, TRPM7 | TAAR1 130/4885NFKB1 3968/4885HTR3A 739/4885 |
| US-20260138987-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | CHRM1, CHRM5, CHRM3 | TAAR1 26/4885NFKB1 4473/4885HTR3A 79/4885 |
| US-20250243208-A1 | BICYCLIC HETEROCYCLES AS MRGPRX2 ANTAGONISTS | MRGPRX2, MRGPRX1, MRGPRX4 | TAAR1 336/4885NFKB1 2305/4885HTR3A 569/4885 |
| US-20250171455-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | CHRM1, CHRM2, CHRM3 | TAAR1 36/4885NFKB1 4390/4885HTR3A 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.