SCHEMBL7350409

SCHEMBL7350409

CC([O])Sc1c(N)cc(N)cc1N

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8675667 0.67 ALDH1A1 (0.38) KDM4EMEN1KMT2ATDP1ALDH1A1
Hydrochloric Acid SCHEMBL8675812 0.65 ALDH1A1 (0.36) KDM4EMEN1KMT2ATDP1ALDH1A1
SCHEMBL7297677 0.65 MAPK1 (0.46) KDM4EMEN1KMT2ATDP1ALDH1A1
SCHEMBL19029861 0.60 CASP1 (0.41) KDM4EMEN1KMT2ATDP1ALDH1A1
SCHEMBL7297946 0.60
SCHEMBL8677466 0.60 PTPN5 (0.39) KDM4EMEN1KMT2AALDH1A1TSHR
SCHEMBL20223487 0.59 CA2 (0.37) ALDH1A1TSHR
SCHEMBL28235815 0.59 FFAR1 (0.48) KDM4EMEN1KMT2ATDP1ALDH1A1
SCHEMBL7350411 0.59
SCHEMBL64498 0.57 TDP1 (0.54) KDM4EMEN1KMT2ATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0602209-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-06-22 EP disclosed
WO-1994001113-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1994-01-20 WO disclosed