SCHEMBL7350671

SCHEMBL7350671

OCc1c(Br)cncc1Br

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 1/20 0.35
PKM P14618 1/20 0.32
KDM4E B2RXH2 2/20 0.31
PDXK O00764 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
POLB P06746 1/20 0.31
RECQL P46063 1/20 0.31
PMP22 Q01453 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14576611 0.85 PDXK (0.39) DRD4KDM4EPDXKALDH1A1HPGD
SCHEMBL28749193 0.84 KDM4E (0.34) KDM4EALDH1A1HPGDHSD17B10
SCHEMBL31394614 0.80
SCHEMBL5554084 0.79 LOX (0.31) PKM
SCHEMBL17573093 0.79
SCHEMBL31394665 0.75 PDXK (0.32) KDM4EPDXKALDH1A1HPGDHSD17B10
SCHEMBL3723951 0.75 CYP11B1 (0.37) KDM4EPOLBCA2
SCHEMBL31470362 0.74
SCHEMBL17802124 0.72
SCHEMBL16213030 0.71 KCNQ2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798943-A Bamboo fiber ecological environment-friendly mulching film and preparation method thereof 福建阳竹新材料科技有限公司 2025-04-11 CN claimed
CN-119798943-A Bamboo fiber ecological environment-friendly mulching film and preparation method thereof 福建阳竹新材料科技有限公司 2025-04-11 CN disclosed
EP-3227300-B1 ALDOSTERONE SYNTHASE INHIBITORS BOEHRINGER INGELHEIM INT (DE) 2019-06-19 EP disclosed
US-10077241-B2 Tetrahydro-benzoimidazolyl modulators of TGR5 JANSEN PHARMACEUTICA NV (BE) 2018-09-18 US disclosed
US-9890171-B2 Aldosterone synthase inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2018-02-13 US disclosed
US-9890171-B2 Aldosterone synthase inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2018-02-13 US disclosed
EP-3227300-A1 ALDOSTERONE SYNTHASE INHIBITORS Boehringer Ingelheim International GmbH (DE) 2017-10-11 EP disclosed
US-20170267688-A1 ALDOSTERONE SYNTHASE INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2017-09-21 US disclosed
US-20170267688-A1 ALDOSTERONE SYNTHASE INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2017-09-21 US disclosed
US-20170267688-A1 ALDOSTERONE SYNTHASE INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2017-09-21 US disclosed
US-20150004712-A1 FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS UNIVERSITY OF OTTAWA (CA) 2015-01-01 US disclosed
US-20150004712-A1 FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS UNIVERSITY OF OTTAWA (CA) 2015-01-01 US disclosed
US-8835641-B2 Fluorescent markers and use thereof for labeling specific protein targets UNIVERSITY OF OTTAWA (CA) 2014-09-16 US disclosed
US-8835641-B2 Fluorescent markers and use thereof for labeling specific protein targets UNIVERSITY OF OTTAWA (CA) 2014-09-16 US disclosed
US-8835641-B2 Fluorescent markers and use thereof for labeling specific protein targets UNIVERSITY OF OTTAWA (CA) 2014-09-16 US disclosed
US-20120171665-A1 FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS UNIVERSITE DE MONTREAL (CA) 2012-07-05 US disclosed
US-20120171665-A1 FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS UNIVERSITE DE MONTREAL (CA) 2012-07-05 US disclosed
US-20120171665-A1 FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS UNIVERSITE DE MONTREAL (CA) 2012-07-05 US disclosed
WO-1997036902-A1 TRANS-2,6-, 3,6- AND 4,6-DIAZA-5,6,6a,7,8,12b-HEXAHYDROBENZO[C]PHENANTHRENE COMPOUNDS AS DOPAMINE AGONISTS ABBOTT LABORATORIES (US) 1997-10-09 WO disclosed
US-5668141-A TREATMENT OF PSYCHOLOGICAL, NEUROLOGICAL AND CARDIOVASCULAR DISORDERS ABBOTT LABORATORIES (US) 1997-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120171665-A1 FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS HNRNPH1, HNRNPH3, HNRNPC DRD4 3559/4885PKM 4657/4885KDM4E 4600/4885
US-20170267688-A1 ALDOSTERONE SYNTHASE INHIBITORS CYP11B1, CYP21A2, CYP11B2 DRD4 3975/4885PKM 852/4885KDM4E 3566/4885
US-20150004712-A1 FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS HNRNPH1, HNRNPH3, HNRNPC DRD4 3559/4885PKM 4657/4885KDM4E 4600/4885
US-10077241-B2 Tetrahydro-benzoimidazolyl modulators of TGR5 GLRA1, GRM5, TRHR DRD4 667/4885PKM 3110/4885KDM4E 950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.