Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338744 | 0.91 | LMNA (0.46) | MAPTLMNASMN1; SMN2PPARGKDR | |
| SCHEMBL7340336 | 0.84 | KDR (0.52) | MAPTLMNASMN1; SMN2PPARGKDR | |
| SCHEMBL6776908 | 0.80 | MAPK1 (0.50) | MAPTLMNASMN1; SMN2PPARGKDR | |
| Chlorobenzene SCHEMBL7832714 | 0.80 | KDM4E (0.52) | MAPTLMNASMN1; SMN2PPARGKDR | |
| SCHEMBL7372561 | 0.80 | KCNK3 (0.56) | MAPTLMNASMN1; SMN2PPARGKDR | |
| SCHEMBL7823595 | 0.79 | KDM4E (0.53) | MAPTLMNASMN1; SMN2KDRKDM4E | |
| SCHEMBL7856448 | 0.78 | PPARG (0.68) | MAPTLMNASMN1; SMN2PPARGKDR | |
| SCHEMBL7861952 | 0.77 | PPARG (0.53) | MAPTLMNASMN1; SMN2PPARGKDR | |
| SCHEMBL7375966 | 0.77 | TSHR (0.45) | MAPTLMNASMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL7341780 | 0.77 | TP53 (0.46) | MAPTLMNASMN1; SMN2PPARGKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1998-07-01 | — | — | EP | claimed |
| WO-1997008145-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-03-06 | — | — | WO | claimed |