Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864782 | 0.86 | MAPT (0.52) | PPARGLMNAMAPTSMN1; SMN2BCHE | |
| SCHEMBL7856497 | 0.84 | MAPT (0.50) | PPARGLMNAMAPTSMN1; SMN2BCHE | |
| SCHEMBL7856448 | 0.83 | PPARG (0.68) | PPARGLMNAMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL7372561 | 0.83 | KCNK3 (0.56) | PPARGLMNAMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL8500095 | 0.79 | PPARG (0.59) | PPARGLMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL7382386 | 0.78 | PPARG (0.63) | PPARGLMNASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL7340336 | 0.77 | KDR (0.52) | PPARGLMNAMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL7350844 | 0.77 | MAPT (0.53) | PPARGLMNAMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL7863258 | 0.77 | PPARG (0.45) | PPARGMAPTBCHEALDH1A1HPGD | |
| SCHEMBL7803055 | 0.76 | KDR (0.58) | LMNAMAPTSMN1; SMN2MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | claimed |