Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbazole SCHEMBL27982238 | 0.89 | ALDH1A1 (0.52) | KIF11ALDH1A1GPR3HSD17B10AHR | |
| SCHEMBL7259924 | 0.87 | MAPT (0.48) | ALDH1A1HSD17B10KDM4EMAPTHTT | |
| SCHEMBL29370549 | 0.85 | MAPT (0.50) | ALDH1A1HSD17B10KDM4EMAOBMAPT | |
| SCHEMBL18172 | 0.85 | MAPT (0.50) | ALDH1A1HSD17B10KDM4EMAOBMAPT | |
| SCHEMBL27392334 | 0.85 | MAPT (0.50) | ALDH1A1HSD17B10KDM4EMAOBMAPT | |
| Methane SCHEMBL11211553 | 0.83 | MAPT (0.48) | ALDH1A1HSD17B10KDM4EMAOBMAPT | |
| Hydrochloric Acid SCHEMBL5370795 | 0.83 | MAPT (0.48) | ALDH1A1HSD17B10KDM4EMAPTHTT | |
| Phosphine SCHEMBL241499 | 0.83 | MAPT (0.48) | ALDH1A1HSD17B10KDM4EMAOBMAPT | |
| SCHEMBL517747 | 0.83 | MAPT (0.48) | ALDH1A1HSD17B10KDM4EMAOBMAPT | |
| Benzene SCHEMBL29053622 | 0.83 | MAPT (0.50) | ALDH1A1HSD17B10KDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588655-B1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| EP-0588655-A1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |