⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23732868 | 0.80 | — | — | |
| Tert-Butyl Formate SCHEMBL27621547 | 0.78 | TDP1 (0.42) | — | |
| SCHEMBL14131007 | 0.78 | NOS2 (0.44) | — | |
| SCHEMBL21263656 | 0.78 | NOS2 (0.44) | — | |
| SCHEMBL129101 | 0.74 | — | — | |
| SCHEMBL1751269 | 0.74 | — | — | |
| SCHEMBL252482 | 0.74 | — | — | |
| SCHEMBL364376 | 0.74 | — | — | |
| SCHEMBL12821996 | 0.74 | — | — | |
| SCHEMBL28229251 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003964-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PYROXASULFONE | ADAMA AGAN LTD (IL) | 2024-09-18 | — | — | EP | disclosed |
| US-20230219937-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | SANOFI (FR) | 2023-07-13 | — | — | US | disclosed |
| US-11059818-B2 | Triazolopyridine inhibitors of myeloperoxidase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-07-13 | — | — | US | disclosed |
| US-20200291015-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL MYERS SQUIBB CO (US) | 2020-09-17 | — | — | US | disclosed |
| EP-0658546-B1 | Novel 3-pyrazolecarboxamide derivatives with cannabinoid receptor affinity | SANOFI SYNTHELABO (FR) | 2001-05-23 | — | — | EP | disclosed |
| US-5462960-A | Very good affinity for cannabinoid receptor; having psycho-tropic activity | SANOFI (FR) | 1995-10-31 | — | — | US | disclosed |
| EP-0658546-A1 | Novel 3-pyrazolecarboxamide derivatives with cannabinoid receptor affinity | SANOFI (FR) | 1995-06-21 | — | — | EP | disclosed |