Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348472 | 0.81 | APEX1 (0.62) | HCRTR1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL8324520 | 0.77 | MEN1 (0.57) | HCRTR1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL11134825 | 0.77 | ALDH1A1 (0.71) | HCRTR1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL28900980 | 0.75 | KMT2A (0.61) | RAB9AKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL21027368 | 0.74 | ALDH1A1 (0.59) | HCRTR1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL8318727 | 0.74 | KDM4E (0.56) | HCRTR1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL5756220 | 0.73 | EGFR (0.48) | KMT2AMAPTMEN1APEX1FFAR4 | |
| SCHEMBL2161298 | 0.73 | HCRTR1 (0.74) | HCRTR1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL22074470 | 0.72 | TRPM8 (0.54) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL27294399 | 0.72 | HCRTR1 (0.58) | HCRTR1RAB9AKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741804-A | Substituted benzimazoles which inhibit platelet aggrecation | SMITHKLINE BEECHAM CORPORATION (US) | 1998-04-21 | — | — | US | disclosed |
| EP-0672034-A4 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION. | SMITHKLINE BEECHAM CORP (US) | 1996-09-25 | — | — | EP | disclosed |
| EP-0672034-A1 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION | SMITHKLINE BEECHAM CORPORATION (US) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994012478-A1 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION | SMITHKLINE BEECHAM CORPORATION (US) | 1994-06-09 | — | — | WO | disclosed |