Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12227421 | 0.78 | CYP1A2 (0.53) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| SCHEMBL8027907 | 0.76 | LTA4H (0.58) | CYP1A2CYP2C19PPARGPPARA | |
| SCHEMBL10885377 | 0.76 | LDHA (0.59) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| SCHEMBL10885375 | 0.76 | LDHA (0.59) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| SCHEMBL10678215 | 0.76 | SLC6A4 (0.68) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| SCHEMBL656814 | 0.75 | SLC6A4 (0.73) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| SCHEMBL7528408 | 0.75 | SLC6A4 (0.73) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| SCHEMBL12104023 | 0.75 | LDHA (0.62) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| SCHEMBL4655986 | 0.75 | LDHA (0.62) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| SCHEMBL13113076 | 0.75 | LDHA (0.62) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767794-B1 | PHOSPHINIC ACID DERIVATIVES | SCHERING CORP (US) | 2000-02-02 | — | — | EP | disclosed |
| US-5476847-A | Treating cardiovascular, gastrointestinal, urogenital disorders | SCHERING CORPORATION (US) | 1995-12-19 | — | — | US | disclosed |