Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15081529 | 0.82 | TSHR (0.56) | TSHRCES1CES2SRCKMT2A | |
| SCHEMBL14868118 | 0.82 | TSHR (0.56) | TSHRCES1CES2SRCKMT2A | |
| SCHEMBL14868116 | 0.82 | TSHR (0.56) | TSHRCES1CES2SRCKMT2A | |
| SCHEMBL28375112 | 0.80 | TSHR (0.54) | TSHRCES1CES2SRCKMT2A | |
| SCHEMBL1158705 | 0.80 | TSHR (0.54) | TSHRCES1CES2SRCKMT2A | |
| SCHEMBL3908247 | 0.79 | CES1 (0.48) | TSHRCES1CES2KMT2AELANE | |
| SCHEMBL9358951 | 0.79 | CES1 (0.48) | TSHRCES1CES2KMT2AELANE | |
| SCHEMBL28374366 | 0.78 | TSHR (0.52) | TSHRCES1CES2SRCKMT2A | |
| SCHEMBL27744142 | 0.77 | CES2 (0.52) | TSHRCES1CES2SRCKMT2A | |
| SCHEMBL27939248 | 0.77 | TSHR (0.50) | TSHRCES1CES2SRCKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993007886-A1 | PHARMACEUTICAL COMPOSITION CONTAINING CERTAIN PEPTIDOMIMETIC COMPOUNDS | ABBOTT LABORATORIES (US) | 1993-04-29 | — | — | WO | disclosed |
| WO-1992022313-A1 | RENIN INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1992-12-23 | — | — | WO | disclosed |
| WO-1991016031-A1 | PSORIASIS TREATMENT | ABBOTT LABORATORIES (US) | 1991-10-31 | — | — | WO | disclosed |