Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8794788 | 0.85 | HPGD (0.64) | HPGDMTNR1ANQO2SIGMAR1 | |
| SCHEMBL9527106 | 0.79 | KDM4E (0.54) | ABCB1HPGDMTNR1A | |
| SCHEMBL8100043 | 0.79 | SIGMAR1 (0.49) | ABCB1HPGDMTNR1ANQO2SIGMAR1 | |
| SCHEMBL11796932 | 0.77 | KCNH2 (0.76) | KCNH2SLC6A4MTNR1ASIGMAR1HTR2A | |
| SCHEMBL13086096 | 0.77 | MTNR1A (0.57) | HPGDMTNR1ANQO2 | |
| SCHEMBL9973174 | 0.76 | KCNH2 (0.60) | KCNH2SLC6A4MTNR1ASIGMAR1HTR2A | |
| SCHEMBL9049841 | 0.76 | SIGMAR1 (0.62) | HPGDMTNR1ASIGMAR1KMT2A | |
| SCHEMBL2343213 | 0.76 | HPGD (0.62) | HPGDMTNR1ANQO2SIGMAR1HTR2A | |
| SCHEMBL19359353 | 0.76 | MPO (0.48) | ABCB1HPGDSLC6A4KMT2A | |
| Hydrochloric Acid SCHEMBL9873692 | 0.76 | HPGD (0.48) | HPGDSLC6A4MTNR1ANQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211244-B1 | AROMATIC AMINES FOR COMPLEXING CALCIUM | NPS PHARMACEUTICALS, INC. | 2001-04-03 | — | — | US | disclosed |