Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MC5R | P33032 | 1/20 | 0.54 |
| ▸ | MC3R | P41968 | 1/20 | 0.54 |
| ▸ | MC1R | Q01726 | 1/20 | 0.54 |
| ▸ | G6PD | P11413 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21225808 | 0.86 | MAPT (0.90) | MAPTTDP1MEN1KMT2ANPC1 | |
| SCHEMBL735125 | 0.83 | MAPT (1.00) | MAPTTDP1MEN1KMT2ANPC1 | |
| SCHEMBL17232881 | 0.79 | MC5R (0.83) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL7970552 | 0.77 | MC5R (0.81) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL6980636 | 0.77 | MEN1 (0.64) | MAPTTDP1MEN1KMT2ANPC1 | |
| SCHEMBL1325639 | 0.77 | HTR2A (0.73) | MEN1KMT2ALMNAHTTMC5R | |
| SCHEMBL9596924 | 0.76 | MAPT (0.67) | MAPTTDP1MEN1KMT2ANPC1 | |
| SCHEMBL7946668 | 0.76 | ACHE (0.74) | ACHE | |
| SCHEMBL9827604 | 0.76 | ACHE (0.69) | ACHE | |
| SCHEMBL1725569 | 0.76 | HTR2A (0.71) | MEN1KMT2ALMNAHTTMC5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515462-A1 | INDOLE DERIVATIVES, THEIR PREPARATION AND USE. | NOVO NORDISK AS (DK) | 1992-12-02 | — | — | EP | disclosed |
| WO-1991012252-A1 | INDOLE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1991-08-22 | — | — | WO | disclosed |