Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4285186 | 0.84 | ALDH1A1 (0.68) | POLBALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL13058838 | 0.81 | POLB (0.64) | POLBALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL7180322 | 0.79 | ALDH1A1 (0.72) | POLBALDH1A1HPGDNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL31323921 | 0.78 | POLB (0.60) | POLBALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL3069389 | 0.78 | ALDH1A1 (0.60) | POLBALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL11754791 | 0.77 | POLB (1.00) | POLBALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL7180515 | 0.77 | ALDH1A1 (0.63) | POLBALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL8434543 | 0.77 | CYP2C19 (0.72) | POLBALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL3183222 | 0.77 | ALDH1A1 (0.79) | POLBALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL10033958 | 0.76 | POLB (0.67) | POLBALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018059-A2 | L-THIAZOLIDINE-4-CARBOXYLIC ACID DERIVATIVE, PROCESSES FOR THE PREPARATION THEREOF AND THE USE THEREOF IN THERAPY | POLI INDUSTRIA CHIMICA S.P.A. (IT) | 1993-09-16 | — | — | WO | claimed |