Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | HPGD | P15428 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351533 | 0.84 | POLB (0.62) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3069389 | 0.82 | ALDH1A1 (0.60) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3183222 | 0.81 | ALDH1A1 (0.79) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29114556 | 0.80 | ALDH1A1 (0.72) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13058838 | 0.78 | POLB (0.64) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3235289 | 0.78 | ALDH1A1 (0.74) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28902578 | 0.77 | MEN1 (0.55) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL711360 | 0.77 | RAB9A (0.75) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2216212 | 0.77 | ALDH1A1 (1.00) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7180322 | 0.77 | ALDH1A1 (0.72) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150657-A1 | IMPROVED PROCESS FOR PREPARATION OF EPTIFIBATIDE BY FMOC SOLID PHASE SYNTHESIS | NATCO PHARMA LIMITED (IN) | 2009-12-17 | — | — | WO | disclosed |