Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.35 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344617 | 0.84 | HTT (0.44) | HTTKMT2AMEN1DPP7SLC1A5 | |
| SCHEMBL7346959 | 0.82 | HTT (0.44) | HTTKMT2AMEN1DPP7HDAC3 | |
| SCHEMBL7353234 | 0.77 | HTT (0.46) | HTTDPP7SLC1A5ALDH1A1LMNA | |
| SCHEMBL7347249 | 0.76 | HTT (0.44) | HTTKMT2AMEN1DPP7SLC1A5 | |
| SCHEMBL7354294 | 0.76 | KMT2A (0.44) | HTTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL7354056 | 0.74 | SLC1A5 (0.38) | HTTAPLNRKMT2ASLC1A5MEP1B | |
| SCHEMBL1343815 | 0.72 | APLNR (0.36) | APLNR | |
| SCHEMBL7352479 | 0.72 | CYP3A4 (0.37) | APLNRL3MBTL1 | |
| SCHEMBL7351671 | 0.72 | APLNR (0.36) | APLNRKMT2A | |
| SCHEMBL11237204 | 0.72 | RIPK1 (0.46) | HTTKMT2AMEN1DPP7HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |